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Can Iron Supplements Lower Your Systolic Blood Pressure?

A study determined the effects of iron supplements during infancy on systolic blood pressure in children born with low birth weight.

Hypertension is one of the most important and, luckily, preventable and curable causes of cardiovascular diseases.

Studies have shown that high systolic blood pressure by the age of 30 can increase the risk of cardiovascular disease by 40%. Lowering the systolic blood pressure by only 5 mmHg can reduce the risk of coronary artery disease by as much as 21%.

There are many underlying causes for the development of hypertension.

Aside from genetics, some pregnancy and birth factors may also play a role in the evolution of this condition.

It has been shown that low birth weight (birth weight less than 2500 g at birth) is related to childhood hypertension.

This difficulty seems more important when we find out that childhood hypertension is a predictor of adulthood hypertension.

In a study published in the American Journal of Clinical Nutrition, researchers in Sweden evaluated the effects of iron supplementation on childhood blood pressure in infants with low birth weight.

The study was a randomized, double-blind, clinical trial in which 285 infants with marginally low birth weight were randomly assigned to one of two groups to receive either a placebo or 1-2 mg of iron supplement from six weeks to six months.

Systolic, diastolic, and prevalence of childhood hypertension were measured and both groups were compared for these parameters.

The mean systolic blood pressure in children who received the placebo was 103 mmHg.

Those who received iron supplements, however, had a lower systolic blood pressure of 101 mmHg. Based on the comparative analysis, the mean systolic blood pressure in children who received iron supplements during infancy was significantly lower than in children who had not received an iron supplement during infancy.

Conclusions from the results

Researchers have concluded that nutritional iron supplementation in children with low birth weight might be helpful in preventing the prevalence of hypertension in childhood and later in life.

Further research can focus on other nutrients that may also play a role in preventing future adult hypertension.

Reference: Lindberg J, Norman M, Westrup B, et al. Lower systolic blood pressure at age 7 y in low-birth-weight children who received iron supplements in infancy: results from a randomized controlled trial. AJCN. 2017 June 28.

Nima Makhdami
Nima Makhdami
Nima has experience as an emergency room physician and clinical research associate. He also has experience in medical literature, clinical data analysis and was a member of a research team for several published articles. He is working on several clinical research projects at the University of Toronto, McMaster University, and Western University. Writing for Medical News Bulletin has allowed Nima to follow his passion for medical writing. He is also passionate about internal medicine and hopes to continue his education in internal medicine residency in the near future. He enjoys playing piano and abstract painting.


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