Rumour: Genetics plays a major role in the acquisition of inflammatory bowel disease (IBD).
Truth: This is true.
Early-onset inflammatory bowel disease (IBD) is a widespread disease affecting an individual’s development, health, and physiological well-being. What differentiates early-onset IBD from adult or infantile-onset is its severity and long-term effects. Research provided an overview of how genetics plays a role in early-onset IBD.
According to the study, close to 200 genes are related to early-onset IBD, with 20-25% of these genes being hereditary. However, due to early-onset IBD’s ability to closely mimic symptoms of those with Crohn’s Disease and other common bowel inflammations, its diagnosis goes undetected.
- Moran CJ, Klein C, Muise AM, Snapper SB. Very early-onset inflammatory bowel disease: gaining insight through focused discovery. Inflamm Bowel Dis. 2015;21(5):1166-1175. doi:10.1097/MIB.0000000000000329