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The Inflammatory Bowel Disease Rumour

Rumour: Genetics plays a major role in the acquisition of inflammatory bowel disease (IBD).

Truth: This is true.

Early-onset inflammatory bowel disease (IBD) is a widespread disease affecting an individual’s development, health, and physiological well-being. What differentiates early-onset IBD from adult or infantile-onset is its severity and long-term effects. Research provided an overview of how genetics plays a role in early-onset IBD.

According to the study, close to 200 genes are related to early-onset IBD, with 20-25% of these genes being hereditary. However, due to early-onset IBD’s ability to closely mimic symptoms of those with Crohn’s Disease and other common bowel inflammations, its diagnosis goes undetected. 

Reference

  1. Moran CJ, Klein C, Muise AM, Snapper SB. Very early-onset inflammatory bowel disease: gaining insight through focused discovery. Inflamm Bowel Dis. 2015;21(5):1166-1175. doi:10.1097/MIB.0000000000000329
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