A recent article published in Biomed Central reports that high dietary intake of saturated fatty acids and cholesterol is associated with low serum albumin and high Hb A1C concentrations.


Cardiovascular disease is classified as the number one cause of morbidity and mortality, with low and middle-income populations being disproportionately affected. Coronary artery bypass grafting surgery (CABG) is considered a therapeutic last resort for patients with coronary artery disease. When the occlusion of coronary arteries is severe enough, surgeons choose bypass grafting over coronary angioplasty and stent placement.

The role of dietary factors and nutrition in prevention and progression of CVD has been extensively studied. A Mediterranean diet is recommended for prevention of cardiovascular disease, due to low saturated fat and high phytochemical content which reduces total and LDL- cholesterol.

The benefits of dietary phytochemical content are evaluated according to the dietary phytochemical index, which reflects the diet quality and cardioprotective character.

A recent cross sectional study published in Biomed Central reported that dietary phytochemical content is associated with serum albumin and HbA1C levels in candidates for CABG surgery.

A total of 454 patients, 35–80 years of age, who were candidates for CABG and hospitalized at Tehran Heart Center in Iran were included in the study. A semi- quantitative questionnaire was filled out by study participants to assess the dietary content.

Based on the results, patients with highly saturated food contents had a lower serum albumin and a higher serum HbA1C levels.

The authors conclude that in candidates for CABG, a high saturated fatty acid content was associated with a lower serum albumin and a higher HbA1 C levels. Additional interventional studies are needed to better evaluate the casual relationship.


Written by: Nima Makhdami, M.D.

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