Investigators in South Korea weigh the safety and effectiveness of a new one-day, multi-faceted method for treating neck wrinkles.
As we age, wrinkles on the neck appear in the form of looser skin and vertical and/or horizontal neck folds. To achieve a lasting reduction of neck wrinkles, a combination of treatment approaches is usually needed. These may include topical retinoids, tissue fillers or activators, thread implantation, fractionated laser treatment, botulinum toxin injection, radiofrequency, and intensity focused ultrasound (IFU) devices.
In a recent South Korean study, published in Dermatologic Surgery, researchers evaluate the safety and efficacy of treating neck wrinkles with a combination of IFU, cohesive polydensified matrix hyaluronic acid (CPMHA, a type of tissue filler), and incobotulinumtoxinA injection (similar to Botox). Twelve South Korean women between the ages of 24 and 50 years old with clinically diagnosed neck wrinkles were enrolled in the study. Patients were excluded from the study if they had received other treatments for neck wrinkles in the previous six months. Participants were first treated with 40 shots of intensity focused ultrasound, followed immediately by CPMHA injection. Finally, incobotulinumtoxinA was injected along the neck folds in a series of about 40 injections spaced one to two centimeters apart.
Improvement of neck wrinkles was assessed using clinical photographs taken at baseline (before treatment) and at one week and one, two, three and six months after treatment. The length of horizontal neck wrinkles was measured and analyzed using these photographs along with computer image analysis software. Two dermatologists (who were not a part of the study) evaluated the overall clinical improvement of neck wrinkles based on the photographs as well.
Overall, the length of horizontal neck wrinkles decreased significantly after treatment. At six months post-treatment, ten of the twelve (83.3%) participants reported being either very satisfied or satisfied with the results of the procedure.
There are many choices for treating neck wrinkles. This study shows that treatment with a combination of approaches effectively targets different aspects of neck wrinkles and reduces their appearance.
Written by Cindi A. Hoover, PhD
Reference: Jeon H, Kim T, Kim H, Cho SB. Multimodal approach for treating horizontal neck wrinkles using intensity focused ultrasound, cohesive polydensified matrix hyaluronic acid, and incobotulinumtoxinA. 2017. Dermatologic Surgery. DOI: 10.1097/DSS.0000000000001312